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 Induced Pluripotent Stem Cells and Epigenetics

  • Dissecting human reprogramming towards pluripotency
  • Epigenetic regulatory mechanisms of cell fate
  • Epigenetic and mechano-sensing related control of cell fate
  • Epigenetic conversion of cell lineage
  • Modelling human diseases with Induced Pluripotent Stem Cells

Paracrine signaling and Extracellular vesicles (EVs)

  • Role of paracrine signaling in Regenerative Medicine
  • EV isolation and quantitation
  • Mesenchymal stem cell-derived EVs for tissue/organ repair
  • EVs for immunotherapy and as immunomodulatory agents
  • EVs in cancer
  • EVs for targeted drug delivery

Mesenchymal stem/stromal cells: holding the promise?

  • Clinical applications: a reassessment
  • GMP production: challenges for public hospitals and for private companies

Tissue and organ reconstruction

Cancer Stem Cells and Stem cell-based therapies for cancer


  • Bioethics of clinical applications
  • Bioethics of research
  • Bioethics of resources, regulations, use of media
  • The role of patient organizations

Additional topics:

  • Cell therapy for myocardial repair
  • Cell Therapy of neurological diseases
  • Cell Therapy of inherited liver metabolic diseases
  • Bioartificial organs: dead or alive?